All southbound lanes on Route 1 in Milford are shut down after a tractor-trailer overturned Monday afternoon.
The crash occurred just before 2:30 p.m. on Route 1 between Cedarhurst Road and the Interstate 95 near Exit 39 A, police said.
Route 1 could be closed for about four hours, while crews remove the vehicle from the scene and investigate the cause of the crash, according to the Department of Transportation.
It is unclear how serious the injuries are.
Drivers are being advised to stay away from the area and Boston Post Road.
Check back with Eyewitness News for updates on this breaking news story.
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