Farmington Avenue in Farmington was closed on Thursday evening following a four-car crash in the area of Farm Glen Boulevard.
Police said the road was shut down between South Road and Talcott Notch Road while crews investigated.
Several people were injured, and two were taken to area hospitals with potentially life-threatening injuries. Another was treated at the scene, but refused transport to the hospital.
Police have not released the identities of those injured.
The road was expected to reopen by 11 p.m.
Anyone with information on the crash should contact police at 860-675-2400.
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